Pharmacological Correction for Adjustment Disorder in Adolescents


  • Valentina A. Gromova
  • Ilya A. Krylov
  • Natalia A. Nazarenko
  • Ludmila E. Gromova
  • Michail Yu. Nazarenko
  • Grigory M. Repnitsyn



The research presents the results of examination and treatment of patients hospitalized in the adolescent male department of the St. Petersburg State Public Healthcare Institution ‘Skvortsov-Stepanov City Psychiatric Hospital No.3’ with diagnosed adjustment disorder. Disorders of emotions and behavior were traced in 80.11% of observations (of which 17.82% were suicidal-blackmailing behavior in the anamnesis, 10.53% with a history of suicide attempts); depressed mood, anxiety, fear attacks in 16.87%, other cases against the background of alcohol and psychoactive substances (PAS) in 3.02%. The main drugs of choice to treat emotional and behavioral disorders with psychomotor disinhibition, aggression, conflict, emotional instability, agitation, anxiety, neurotic signs (symptoms), and sleep disorders are: thioridazine, pericyazine, chlorprothixene, sulpiride (eglonyl). In 94.51% of cases, the treatment was effective – the condition was improved to complete remission of the symptoms that dominated on admission and in the first days. Decompensation was observed in 3.61% of cases due to refusal to receive maintenance therapy.