Volume 11 - Volume 11
Approaches to the Treatment of Diseases of Distal Limb Parts in Cattle
Abstract
Mortellaro’s disease affects up to 25% of Russia's cattle, which causes significant economic damage
to dairy products. The indicators of the therapeutic efficacy of existing drugs vary, and obsolete
agents and schemes are used for treatment. A drug was developed and tested using the technology
of liposomal silver nanoparticles (Ag) for treatment of Mortellaro’s disease in dairy cows. By
comparison and grouping method, the effectiveness of 5 drug samples at different stages of
development of infectious and pathological processes in 5 experimental groups of cows was
compared with 2 control groups: Group 1 received no treatment, Group 2 was treated with Solka
Hoofgel. It was established that sample 2 of the developed preparation with Ag content of 15 ml
showed 92-96% of the therapeutic efficacy in the treatment of Mortellaro’s disease, which is higher
than that of the analog preparation by 25%. The drug provides the appearance of granulation tissue
in the affected areas as early as the fifth day after application to the damaged surface of the
interdigital space and the epithelization of the damaged areas after 7 days of treatment.
Paper Details
PaperID: 1644
Author's Name: A.M. Kovalenko, N.V. Yavnikov, S.A. Khomutovskaya and N.A. Belyakova
Volume: Volume 11
Issues: Volume 11
Keywords: Mortellaro Disease, Ag Nanoparticles, Cows.
Year: 2021
Month: April
Pages: 61-70